the role of helicobacter pylori in development of gastric cancer
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the role of helicobacter pylori in development of gastric cancer
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The Role of Helicobacter Pylori Virulence Factors in Gastric Cancer
Introduction: Gastrointestinal (GI) cancers are considered among the most important causes of mortality and morbidity. Helicobacter pylori infection has been proven to be highly associated with the development of a variety of gastric diseases such as chronic gastritis, peptic ulcer disease (PUD), mucosa-associated lymphoid tissue (MALT), and gastric cancer (GC). To date, the exact role of the v...
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15 صفحه اولRole of autophagy associated with Helicobacter pylori CagA and VacA toxins in gastric cancer
Helicobacter pylori (H. pylori) is a gram-negative microaerophilic bacterium that has been introduced as a cause of mucosal inflammation and gastric cancer. The most important pathogenic factors are VacA and CagA, which are associated with increased disease severity in clinical strains. Autophagy is a protected lysosomal degradation pathway degrading cytoplasmic content and is important in host...
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15 صفحه اولHelicobacter pylori infection and the development of gastric cancer.
BACKGROUND Although many studies have found an association between Helicobacter pylori infection and the development of gastric cancer, many aspects of this relation remain uncertain. METHODS We prospectively studied 1526 Japanese patients who had duodenal ulcers, gastric ulcers, gastric hyperplasia, or nonulcer dyspepsia at the time of enrollment; 1246 had H. pylori infection and 280 did not...
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گوارشجلد ۷، شماره ۴۱، صفحات ۱۳۲-۰
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